Neuropathy can be reduced with acupuncture. About Peripheral Neuropathy Common causes of peripheral neuropathy include diabetes, vitamin B12 deficiency, lyme disease, chemotherapy, and thyroid disorders.  However, one third of peripheral neuropathy cases have no known cause, even after an exhaustive medical exam.  It is estimated that over 20 million Americans suffer from some form of peripheral neuropathy and can be described as tingling, numbness, or pain in the hands and f